BDBM286029 2-Chloro-N-(2(4-fluorophenyl)-1-methyl-1H-indol-5-yl)-5-((2,2-dimethylpropanoylamino)methyl)benzamide::US10081629, Example 11

SMILES Cn1c(cc2cc(NC(=O)c3cc(CNC(=O)C(C)(C)C)ccc3Cl)ccc12)-c1ccc(F)cc1

InChI Key InChIKey=FBLVYPVLNUAIJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286029   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286029(US10081629, Example 11 | 2-Chloro-N-(2(4-fluorophe...)
Affinity DataIC50: 5.14nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286029(US10081629, Example 11 | 2-Chloro-N-(2(4-fluorophe...)
Affinity DataIC50: 16.3nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286029(US10081629, Example 11 | 2-Chloro-N-(2(4-fluorophe...)
Affinity DataIC50: 16.3nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In DepthDetails
US Patent