BDBM286026 2-Chloro-N-(1-ethyl-2-(4-fluorophenyl)-1H-indol-5-yl)5-((2,2-dimethylpropanoylamino)methyl)-benzamide::US10081629, Example 8

SMILES CCn1c(cc2cc(NC(=O)c3cc(CNC(=O)C(C)(C)C)ccc3Cl)ccc12)-c1ccc(F)cc1

InChI Key InChIKey=JFJMIXXNHLPQMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286026   

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286026(US10081629, Example 8 | 2-Chloro-N-(1-ethyl-2-(4-f...)
Affinity DataIC50: 3.88nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286026(US10081629, Example 8 | 2-Chloro-N-(1-ethyl-2-(4-f...)
Affinity DataIC50: 19.1nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2019
Entry Details
Go to US Patent