BDBM2857 1-(5-bromopyridin-2-yl)-3-[(1R,2R)-2-phenylcyclopropyl]thiourea::PETT deriv. 7

SMILES Brc1ccc(NC(=S)N[C@@H]2C[C@@H]2c2ccccc2)nc1

InChI Key InChIKey=WDYJSZQUBJOQCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2857   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2857(1-(5-bromopyridin-2-yl)-3-[(1R,2R)-2-phenylcyclopr...)
Affinity DataIC50: 8nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2005
Entry Details Article
PubMed