BDBM2856 5-bromo-1-[(1R,2R)-2-phenylcyclopropyl]pyridine-2-guanidine::PETT deriv. 6

SMILES NC(Nc1ccc(Br)cn1)=N[C@@H]1C[C@@H]1c1ccccc1

InChI Key InChIKey=ZUSWXAUTXLMRDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2856   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2856(5-bromo-1-[(1R,2R)-2-phenylcyclopropyl]pyridine-2-...)
Affinity DataIC50: 180nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2005
Entry Details Article
PubMed