BDBM285590 1-{3-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazin-3-yl]-4-fluoro-phenyl}ethanone, formate salt::US10077269, Example 63::US10669279, Example 63::US9598421, Example 63

SMILES CC(=O)c1ccc(F)c(c1)-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=QERGAMABSQIOLR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 285590   

LigandPNGBDBM285590(US10077269, Example 63 | 1-{3-[2-(azetidin-1-ylcar...)
Affinity DataIC50: 17.7nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285590(US10077269, Example 63 | 1-{3-[2-(azetidin-1-ylcar...)
Affinity DataIC50: 394nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285590(US10077269, Example 63 | 1-{3-[2-(azetidin-1-ylcar...)
Affinity DataIC50: 17.7nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285590(US10077269, Example 63 | 1-{3-[2-(azetidin-1-ylcar...)
Affinity DataIC50: 394nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285590(US10077269, Example 63 | 1-{3-[2-(azetidin-1-ylcar...)
Affinity DataIC50: 17.7nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285590(US10077269, Example 63 | 1-{3-[2-(azetidin-1-ylcar...)
Affinity DataIC50: 394nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent