BDBM285556 3-(4-chloro-3-fluorophenyl)-N-propylimidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 29::US10669279, Example 29::US9598421, Example 29

SMILES CCCNC(=O)c1nc2cccnn2c1-c1ccc(Cl)c(F)c1

InChI Key InChIKey=ZOPYTZDTLDQKKZ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285556   

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 3.48nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 5.05nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 13.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 409nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 3.48nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 5.05nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 13.8nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 409nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 3.48nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 5.05nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 13.8nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285556(US10077269, Example 29 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 409nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent