BDBM285528 Azetidin-1-yl[3-(4-chlorophenyl)imidazo[1,2-b]pyridazin-2-yl]methanone (1)::US10077269, Example 1::US10669279, Example 1

SMILES Clc1ccc(cc1)-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=OUXBYUBGWJQGHZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 285528   

LigandPNGBDBM285528(US10077269, Example 1 | Azetidin-1-yl[3-(4-chlorop...)
Affinity DataIC50: 38.6nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285528(US10077269, Example 1 | Azetidin-1-yl[3-(4-chlorop...)
Affinity DataIC50: 35.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285528(US10077269, Example 1 | Azetidin-1-yl[3-(4-chlorop...)
Affinity DataIC50: 130nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285528(US10077269, Example 1 | Azetidin-1-yl[3-(4-chlorop...)
Affinity DataIC50: 1.03E+4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285528(US10077269, Example 1 | Azetidin-1-yl[3-(4-chlorop...)
Affinity DataIC50: 38.6nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285528(US10077269, Example 1 | Azetidin-1-yl[3-(4-chlorop...)
Affinity DataIC50: 35.5nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285528(US10077269, Example 1 | Azetidin-1-yl[3-(4-chlorop...)
Affinity DataIC50: 130nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM285528(US10077269, Example 1 | Azetidin-1-yl[3-(4-chlorop...)
Affinity DataIC50: 1.03E+4nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In DepthDetails
US Patent