BDBM2855 1-[2-(2-methoxyphenyl)ethyl]-3-1,3-thiazol-2-ylthiourea::PETT Analog 5::PETT deriv. 5

SMILES COc1ccccc1CCNC(=S)Nc1nccs1

InChI Key InChIKey=MRSDMFHPBHPUME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2855   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2855(PETT Analog 5 | 1-[2-(2-methoxyphenyl)ethyl]-3-1,3...)
Affinity DataIC50: 40nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2855(PETT Analog 5 | 1-[2-(2-methoxyphenyl)ethyl]-3-1,3...)
Affinity DataIC50: 40nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2005
Entry Details Article
PubMed