BDBM2854 2-cyano-3-[2-(2-methoxyphenyl)ethyl]-1-1,3-thiazol-2-ylguanidine::PETT deriv. 4

SMILES COc1ccccc1CCN=C(NC#N)Nc1nccs1

InChI Key InChIKey=HCMKWAKBCQRZMQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2854   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2854(2-cyano-3-[2-(2-methoxyphenyl)ethyl]-1-1,3-thiazol...)
Affinity DataIC50: 1.00E+4nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2005
Entry Details Article
PubMed