BDBM283872 US10023562, Example 64::US10544133, Example 64::US9657009, 64

SMILES CC(C)Nc1cc(Nc2ncc(cc2F)C#N)ncc1C(=O)NCC[C@@H](C)NC(C)=O

InChI Key InChIKey=UQYIDHRAEXIXJE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 283872   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM283872(US10023562, Example 64 | US9657009, 64 | US1054413...)
Affinity DataIC50: 3.10nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM283872(US10023562, Example 64 | US9657009, 64 | US1054413...)
Affinity DataIC50: 3.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM283872(US10023562, Example 64 | US9657009, 64 | US1054413...)
Affinity DataIC50: 3.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In DepthDetails
US Patent