BDBM283857 US10023562, Example 49::US10544133, Example 49::US9657009, 49

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(Nc2ncc(cc2F)C#N)cc1NC1CCOCC1

InChI Key InChIKey=PKAOYSDCGJLPSC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 283857   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM283857(US10023562, Example 49 | US9657009, 49 | US1054413...)
Affinity DataIC50: 3.10nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM283857(US10023562, Example 49 | US9657009, 49 | US1054413...)
Affinity DataIC50: 3.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM283857(US10023562, Example 49 | US9657009, 49 | US1054413...)
Affinity DataIC50: 3.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In DepthDetails
US Patent