BDBM283710 N-[4-(azetidin-3-ylsulfanyl)phenyl]-4-chloro-3-cyclopropyl-1H-pyrazole-5-carboxamide::US10023559, Example 35

SMILES Clc1c(n[nH]c1C(=O)Nc1ccc(SC2CNC2)cc1)C1CC1

InChI Key InChIKey=NRPWCRGNSNFJFV-UHFFFAOYSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283710   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM283710(N-[4-(azetidin-3-ylsulfanyl)phenyl]-4-chloro-3-cyc...)
Affinity DatapH: 7.4Assay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM283710(N-[4-(azetidin-3-ylsulfanyl)phenyl]-4-chloro-3-cyc...)
Affinity DataKi:  47nMpH: 7.4Assay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In DepthDetails
US Patent