BDBM282901 6-(1-(3,3-difluorocyclobutyl)-4-(4-fluorophenyl)-1H- imidazol-5-yl)imidazo[1,2-b]pyridazine-3-carboxamide::US10287295, Example 111'::US11352360, Example 106'::US9884868, Example 106'
SMILES NC(=O)c1cnc2ccc(nn12)-c1c(ncn1C1CC(F)(F)C1)-c1ccc(F)cc1
InChI Key InChIKey=FKAOOXULXXUYOX-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 282901
Affinity DataIC50: 6.10nMpH: 7.4 T: 2°CAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair