BDBM2809 Alkenyldiarylmethanes (ADAM) 6b::CHEMBL105859::Methyl (5Z)-6-(3,4-dimethoxyphenyl)-6-[4-methoxy-3-(methoxycarbonyl)-5-methylphenyl]hex-5-enoate::methyl 5-[(1E)-1-(3,4-dimethoxyphenyl)-6-methoxy-6-oxohex-1-en-1-yl]-2-methoxy-3-methylbenzoate

SMILES COC(=O)CCC\C=C(\c1ccc(OC)c(OC)c1)c1cc(C)c(OC)c(c1)C(=O)OC

InChI Key InChIKey=WNKWNLLPIAKZAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2809   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2809(Methyl (5Z)-6-(3,4-dimethoxyphenyl)-6-[4-methoxy-3...)
Affinity DataIC50: 74nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM2809(Methyl (5Z)-6-(3,4-dimethoxyphenyl)-6-[4-methoxy-3...)
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed