BDBM28045 4-(4-iodophenoxy)thieno[2,3-c]pyridine-2-carboxylic acid::CHEMBL523921::thieno[2,3-c]pyridine, 1

SMILES OC(=O)c1cc2c(Oc3ccc(I)cc3)cncc2s1

InChI Key InChIKey=NANXSYXGMOHIFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28045   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM28045(CHEMBL523921 | 4-(4-iodophenoxy)thieno[2,3-c]pyrid...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:The COT direct HTRF assay was carried out using biotin-MEK1 as a substrate. The reaction was carried out in black 96 half-well plates. At designated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM28045(CHEMBL523921 | 4-(4-iodophenoxy)thieno[2,3-c]pyrid...)
Affinity DataIC50: 940nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed