BDBM27945 uridine derivative, 42::{[(2R,3S,4R,5R)-5-(6-amino-5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

SMILES Nc1c(F)c(=O)[nH]c(=O)n1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O

InChI Key InChIKey=OLBMCLUPWOAIRA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27945   

TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM27945({[(2R,3S,4R,5R)-5-(6-amino-5-fluoro-2,4-dioxo-1,2,...)
Affinity DataKi:  1.14E+4nM ΔG°:  -7.42kcal/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUridine 5'-monophosphate synthase(Human)
Toronto General Research Institute

LigandPNGBDBM27945({[(2R,3S,4R,5R)-5-(6-amino-5-fluoro-2,4-dioxo-1,2,...)
Affinity DataKi:  1.66E+4nM ΔG°:  -6.78kcal/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed