BDBM27905 8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(ethanesulfonyl)ethyl]phenyl}amino)-N-methoxy-5-oxo-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxamide::Pyrido[2,3-d]pyrimidin-5-one, 33

SMILES CONC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(CCS(=O)(=O)NC(C)=O)cc3)ncc2c1=O

InChI Key InChIKey=ZVKLAKFTPJGJCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27905   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM27905(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(ethanesulf...)
Affinity DataIC50: 2.40nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2009
Entry Details Article
PubMed