BDBM278452 US10040788, Example 31(b)

SMILES CCO[C@H](C(=O)Nc1nnc(N[C@H]2CCN(C2)c2cccnn2)s1)c1ccc(F)c(OC)c1

InChI Key InChIKey=IYPATRWUVVTXAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 278452   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

US Patent
LigandPNGBDBM278452(US10040788, Example 31(b))
Affinity DataIC50: 86.2nMpH: 7.8Assay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2018
Entry Details
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