BDBM276080 1-(cyclopropylmethyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}-1H-imidazole::US10071984, Example 42::US10174003, Example 42::US9896436, Example 42

SMILES C(C1CC1)n1cnc(c1)-c1cc2[nH]nnc2cn1

InChI Key InChIKey=JKQLIDDJQPWZHO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276080   

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276080(1-(cyclopropylmethyl)-4-{1H-[1,2,3]triazolo[4,5-c]...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276080(1-(cyclopropylmethyl)-4-{1H-[1,2,3]triazolo[4,5-c]...)
Affinity DataIC50: 5.50E+3nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276080(1-(cyclopropylmethyl)-4-{1H-[1,2,3]triazolo[4,5-c]...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetHistone lysine demethylase PHF8(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276080(1-(cyclopropylmethyl)-4-{1H-[1,2,3]triazolo[4,5-c]...)
Affinity DataIC50: 500nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent