BDBM276074 4-(5-chloro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyridine::US10071984, Example 36::US10174003, Example 36::US9896436, Example 36

SMILES Clc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1

InChI Key InChIKey=PEMXJDNZTLRVBK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276074   

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276074(4-(5-chloro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276074(4-(5-chloro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...)
Affinity DataIC50: 5.50E+3nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276074(4-(5-chloro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone lysine demethylase PHF8(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276074(4-(5-chloro-1H-triazol-4-yl)-2-[1-(2-naphthalen-1-...)
Affinity DataIC50: 500nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
In DepthDetails
US Patent