BDBM276057 2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-(5-iodo-1H-triazol-4-yl)pyridine::US10071984, Example 19::US10174003, Example 19::US9896436, Example 19

SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2I)c1Cl

InChI Key InChIKey=KJZSHAPRNVEXAD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276057   

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276057(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276057(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276057(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone lysine demethylase PHF8(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM276057(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Affinity DataIC50: 300nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
In DepthDetails
US Patent