BDBM27592 2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-1H-pyrazol-5-yl]sulfanyl}acetamido)phenyl]phenyl}acetic acid::pyrazolyl compound, 29

SMILES Cc1ccc(c(Cl)c1)-n1nccc1SCC(=O)Nc1ccc(cc1Cl)-c1ccc(CC(O)=O)cc1

InChI Key InChIKey=JQEHHYUUNKMJPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27592   

TargetGag-Pol polyprotein [588-1027](HIV-1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27592(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 7.90nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27592(2-{4-[3-chloro-4-(2-{[1-(2-chloro-4-methylphenyl)-...)
Affinity DataIC50: 420nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed