BDBM2759 1-Bromo-4,4-bis[8,8-dichloro-2,2,2,2-tetramethyl-4,4-dioxo-6,6-(1,3-benzodioxyl)]-3-butene::6-[4-bromo-1-(8-chloro-2,2-dimethyl-4-oxo-2,4-dihydro-1,3-benzodioxin-6-yl)but-1-en-1-yl]-8-chloro-2,2-dimethyl-2,4-dihydro-1,3-benzodioxin-4-one::Alkenyldiarylmethane (ADAM) 35::Alkenyldiarylmethanes (ADAM) 35

SMILES [#6]C1([#6])[#8]-[#6](=O)-c2cc(cc(Cl)c2-[#8]1)-[#6](=[#6]/[#6]-[#6]Br)\c1cc(Cl)c2-[#8]C([#6])([#6])[#8]-[#6](=O)-c2c1

InChI Key InChIKey=JRRLEWQOBRSSER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2759   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2759(6-[4-bromo-1-(8-chloro-2,2-dimethyl-4-oxo-2,4-dihy...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed