BDBM2758 8-chloro-6-[1-(8-chloro-2,2-dimethyl-4-oxo-2,4-dihydro-1,3-benzodioxin-6-yl)-4-hydroxybut-1-en-1-yl]-2,2-dimethyl-2,4-dihydro-1,3-benzodioxin-4-one::Alkenyldiarylmethane (ADAM) 34::Alkenyldiarylmethanes (ADAM) 34

SMILES [#6]C1([#6])[#8]-[#6](=O)-c2cc(cc(Cl)c2-[#8]1)-[#6](=[#6]/[#6]-[#6]-[#8])\c1cc(Cl)c2-[#8]C([#6])([#6])[#8]-[#6](=O)-c2c1

InChI Key InChIKey=RCEJPDLLLDRXMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2758   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2758(8-chloro-6-[1-(8-chloro-2,2-dimethyl-4-oxo-2,4-dih...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2004
Entry Details Article
PubMed