BDBM275768 CYCLIC CIDOFOVIR::Cyclic-hpmpc::US10071110, Compound Cyclic Cidofovir (cDCV)::US10071110, Compound cCDV

SMILES Nc1ccn(CC2COP(O)(=O)CO2)c(=O)n1

InChI Key InChIKey=YXQUGSXUDFTPLL-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 275768   

TargetFibroblast growth factor receptor 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  470nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  970nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFibroblast growth factor receptor 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  720nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHIV-1 protease(Human immunodeficiency virus)
The Regents of The University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  2.10E+3nMAssay Description:Subconfluent MRC-5 cells in 24-well culture dishes were inoculated by removing the medium and adding HSV-1 virus at a dilution that will result in a ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCapsid scaffolding protein(HHV-5)
The Regents of The University of California

US Patent
LigandPNGBDBM275768(CYCLIC CIDOFOVIR | US10071110, Compound Cyclic Cid...)
Affinity DataEC50:  470nMAssay Description:Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...More data for this Ligand-Target Pair
In DepthDetails
US Patent