BDBM274455 2-fluoro-N-(6-(4-(4-fluorophenyl)-1-(1- ((5-methylisoxazol-3- yl)methyl)piperidin-4-yl)-1H-imidazol- 5-yl)imidazo[1,2-b]pyridazin-2- yl)isonicotinamide::US9556179, Compound 24

SMILES Cc1cc(CN2CCC(CC2)n2cnc(c2-c2ccc3nc(NC(=O)c4ccnc(F)c4)cn3n2)-c2ccc(F)cc2)no1

InChI Key InChIKey=STOYCNWIXUKKEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 274455   

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274455(2-fluoro-N-(6-(4-(4-fluorophenyl)-1-(1- ((5-methyl...)
Affinity DataIC50: 0.183nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274455(2-fluoro-N-(6-(4-(4-fluorophenyl)-1-(1- ((5-methyl...)
Affinity DataIC50: 0.165nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In DepthDetails
US Patent