BDBM273003 (2S,3S)-1-(1-(2- aminobenzo[d]oxazol- 5-yl)-8,9-dihydro-7H-6- oxa-2,9a- diazabenzo[cd]azulen- 4-yl)-3- methylpyrrolidine-2- carboxamide::US10065970, Example 308::US10065970, Example 309::US10435414, Example 309

SMILES C[C@H]1CCN([C@@H]1C(N)=O)c1cc2OCCCCn3c(nc(c1)c23)-c1ccc2oc(N)nc2c1

InChI Key InChIKey=BZTXFWHVZWNGGP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 273003   

LigandPNGBDBM273003(US10065970, Example 309 | (2S,3S)-1-(1-(2- aminobe...)
Affinity DataKi:  0.0400nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
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LigandPNGBDBM273003(US10065970, Example 309 | (2S,3S)-1-(1-(2- aminobe...)
Affinity DataKi:  0.0400nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

LigandPNGBDBM273003(US10065970, Example 309 | (2S,3S)-1-(1-(2- aminobe...)
Affinity DataKi:  0.627nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent