BDBM270880 US10059709, 26

SMILES CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1c(cnc2[nH]ccc12)C#N

InChI Key InChIKey=WMFAFHAAENZTGM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 270880   

TargetTyrosine-protein kinase JAK1(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270880(US10059709, 26)
Affinity DataIC50: 34nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270880(US10059709, 26)
Affinity DataIC50: 3.00E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270880(US10059709, 26)
Affinity DataIC50: 840nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent