BDBM27088 1H-1,3-benzodiazole-4-carboxamide::1H-benzimidazole-4-carboxamide, 1::CHEMBL133694

SMILES NC(=O)c1cccc2nc[nH]c12

InChI Key InChIKey=JJDMKDXGNVJWCD-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 27088   

TargetPoly [ADP-ribose] polymerase 1(Human)
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM27088(1H-1,3-benzodiazole-4-carboxamide | CHEMBL133694 |...)
Affinity DataIC50: 240nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM27088(1H-1,3-benzodiazole-4-carboxamide | CHEMBL133694 |...)
Affinity DataKi:  95nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM27088(1H-1,3-benzodiazole-4-carboxamide | CHEMBL133694 |...)
Affinity DataKi:  240nM ΔG°:  -8.93kcal/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM27088(1H-1,3-benzodiazole-4-carboxamide | CHEMBL133694 |...)
Affinity DataKi:  240nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed