BDBM270875 US10059709, 21

SMILES CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1nc(N)ncc1-c1ccccc1

InChI Key InChIKey=TWVMFQJHNOMQHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 270875   

TargetTyrosine-protein kinase JAK1(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270875(US10059709, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270875(US10059709, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270875(US10059709, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In DepthDetails
US Patent