BDBM270872 US10059709, 18

SMILES CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1c(cnc2[nH]ccc12)[N+]([O-])=O

InChI Key InChIKey=MLXWTGBMWKWFQN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 270872   

TargetTyrosine-protein kinase JAK1(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270872(US10059709, 18)
Affinity DataIC50: 21nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270872(US10059709, 18)
Affinity DataIC50: 1.20E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270872(US10059709, 18)
Affinity DataIC50: 390nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent