BDBM26682 2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-carbonitrile::2-amino-6-(4-ketocyclohexa-2,5-dien-1-ylidene)-4-phenyl-1H-pyridine-3-carbonitrile::2-aminopyridine-3-carbonitrile, 10

SMILES Nc1nc(cc(-c2ccccc2)c1C#N)-c1ccc(O)cc1

InChI Key InChIKey=VVFRJCXNTHXSOG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26682   

TargetSerine/threonine-protein kinase pim-1(Human)
Valeant Pharmaceuticals Research and Development

LigandPNGBDBM26682(2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-car...)
Affinity DataIC50: 4.41E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed
TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM26682(2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-car...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM23(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM26682(2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-car...)
Affinity DataIC50: 2.90E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM26682(2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-car...)
Affinity DataIC50: 1.03E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM26682(2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-car...)
Affinity DataIC50: 4.52E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay