BDBM264723 US9718792, 2-A

SMILES CC#Cc1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1

InChI Key InChIKey=FCHOBKLAYAXQCL-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264723   

TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Novartis

US Patent
LigandPNGBDBM264723(US9718792, 2-A)
Affinity DataIC50: 0.00100nMpH: 7.5 T: 2°CAssay Description:The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Novartis

US Patent
LigandPNGBDBM264723(US9718792, 2-A)
Affinity DataKd:  0.440nMAssay Description:Binding affinity to Pseudomonas aeruginosa PAO1 NB52019 LpxC after 60 to 420 secs by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed