BDBM264468 5-(3H-spiro[isobenzofuran-1,4'-piperidin]-1'-yl)-2-(thiazol-2-yl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide::US9714252, 4

SMILES O=S1(=O)N(Cc2cc(ccc12)N1CCC2(CC1)OCc1ccccc21)c1nccs1

InChI Key InChIKey=FXFKUVOTAPXMIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264468   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM264468(5-(3H-spiro[isobenzofuran-1,4'-piperidin]-1'-yl)-2...)
Affinity DataIC50: 1.38E+3nMAssay Description:Representative Compounds of the Invention have been tested in the FLIPR, FLIPRTETRA, and/or electrophysiology (EP) assays for sodium channel blocking...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
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