BDBM264467 5-(4-chloro-2-(1-methyl-1H-pyrazol-5-yl)phenoxy)-2-(thiazol-2-yl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide::US9714252, 3

SMILES Cn1nccc1-c1cc(Cl)ccc1Oc1ccc2c(CN(c3nccs3)S2(=O)=O)c1

InChI Key InChIKey=JGDJUDRCLGDGQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264467   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM264467(5-(4-chloro-2-(1-methyl-1H-pyrazol-5-yl)phenoxy)-2...)
Affinity DataIC50: 9.10E+3nMAssay Description:Representative Compounds of the Invention have been tested in the FLIPR, FLIPRTETRA, and/or electrophysiology (EP) assays for sodium channel blocking...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
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