BDBM263361 US9546162, 19

SMILES COc1cc(CO)cc(c1)S(=O)(=O)N1CCc2cccc(CCc3ccc(cc3)C(O)=O)c12

InChI Key InChIKey=GNQFVWHBHKWCJW-UHFFFAOYSA-N

Data  4 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 263361   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM263361(US9546162, 19)
Affinity DataKi:  0.400nM EC50:  2nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM263361(US9546162, 19)
Affinity DataKi:  18nM EC50:  36nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM263361(US9546162, 19)
Affinity DataKi:  776nMpH: 7.4Assay Description:Cells were seeded at a density of 5×104 cells per well in Biocoat Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM263361(US9546162, 19)
Affinity DataKi:  8.23E+3nM EC50: >1.00E+4nMpH: 7.4Assay Description:Cells were seeded at a density of 5×104 cells per well in Biocoat Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
Go to US Patent