BDBM263349 US9546162, 7

SMILES OC(=O)c1ccc(CCc2cccc3CCN(Cc4cc(OCc5ccccc5)cc(OCc5ccccc5)c4)c23)cc1

InChI Key InChIKey=PSEUTBLHHIUSPT-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263349   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM263349(US9546162, 7)
Affinity DataEC50:  5.85E+3nMpH: 7.4Assay Description:Cells were seeded at a density of 5×104 cells per well in Biocoat Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM263349(US9546162, 7)
Affinity DataKi:  20nM EC50:  161nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM263349(US9546162, 7)
Affinity DataKi:  34nM EC50:  33nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
Go to US Patent