BDBM26311 3-[4-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)phenyl]-1-[3-(trifluoromethyl)phenyl]urea::CHEMBL461999::thieno[3,2-d]pyrimidine analogue, 6

SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(CCNc3ncnc4ccsc34)cc2)c1

InChI Key InChIKey=UZICNABHDZJWBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26311   

TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26311(CHEMBL461999 | 3-[4-(2-{thieno[3,2-d]pyrimidin-4-y...)
Affinity DataIC50: 1.20E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26311(CHEMBL461999 | 3-[4-(2-{thieno[3,2-d]pyrimidin-4-y...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed