BDBM26196 4-cyanophenol::4-hydroxybenzonitrile::phenol derivative, 10

SMILES Oc1ccc(cc1)C#N

InChI Key InChIKey=CVNOWLNNPYYEOH-UHFFFAOYSA-N

Data  15 KI  1 ITC

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 26196   

TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  108nM ΔG°:  -9.50kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  108nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 3(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  6.70E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  9.20E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  1.37E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  2.91E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 13(Mouse)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  4.50E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  5.60E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  1.31E+5nM ΔG°:  -5.29kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  6.34E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  5.20E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  7.77E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  5.57E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  4.34E+5nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
Affinity DataKi:  1.31E+5nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 26196   

HostPNGBDBM36284(SAMPL3, H3 | BDBM36303 | Methyl Viologen-Cucurbit[...)
University of Cambridge

GuestPNGBDBM26196(4-cyanophenol | 4-hydroxybenzonitrile | phenol der...)
ITC DataΔG°: -4.78kcal/mole logk: 3.20E+3
pH: 7.0 T: 25.00°C