BDBM261711 US9708295, 53

SMILES CCOc1cc(ncc1-c1cnc(N)c(O[C@H](C)c2c(Cl)ccc(F)c2Cl)c1)N1CCNC[C@@H]1C

InChI Key InChIKey=FSOVRVNYQVYZPX-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 261711   

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM261711(US9708295, 53)
Affinity DataIC50: 13.9nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetTyrosine-protein kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM261711(US9708295, 53)
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetTyrosine-protein kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM261711(US9708295, 53)
Affinity DataKi:  4.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM261711(US9708295, 53)
Affinity DataKi:  32.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [G1269S](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM261711(US9708295, 53)
Affinity DataKi:  115nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent