BDBM259805 US9505766, CN-OMe (4)

SMILES COC(=O)C(=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO)\C#N

InChI Key InChIKey=GDXHZXJALWQIPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259805   

TargetRibosomal protein S6 kinase alpha-3 [399-740](Human)
University of California

US Patent
LigandPNGBDBM259805(US9505766, CN-OMe (4))
Affinity DataIC50: 13nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetRibosomal protein S6 kinase alpha-3 [399-740,C436V](Human)
University of California

US Patent
LigandPNGBDBM259805(US9505766, CN-OMe (4))
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent