BDBM259366 US9505745, 43::US9790212, Example 43

SMILES CCC([C@H]1CC[C@H](N)CC1)c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C

InChI Key InChIKey=LQRSUXVZQNCRKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259366   

LigandPNGBDBM259366(US9505745, 43 | US9790212, Example 43)
Affinity DataIC50: 16nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM259366(US9505745, 43 | US9790212, Example 43)
Affinity DataIC50: 16nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
In DepthDetails
US Patent