BDBM25887 (2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2-(thiophen-2-ylformamido)butanamide::N-heterocyclic dipeptide aldehyde, 5

SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1cccs1)C(C)C)C=O

InChI Key InChIKey=KAWBOPKLHZHXET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25887   

TargetCalpain-1 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25887((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50: 680nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25887((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed