BDBM258123 US9493448, 25::US9597330, Example 3::US9845313, Example 49

SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1

InChI Key InChIKey=CEHAIZRVGILZFK-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 258123   

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 95nMpH: 7.3 T: 2°CAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 95nMAssay Description:Current recording was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 95nMAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 660nMAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.1/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human NaV1.5/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 113nMAssay Description:Inhibition of human NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-2(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 400nMAssay Description:Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM258123(US9493448, 25 | US9597330, Example 3 | US9845313, ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by Ionworks high-throughput electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed