BDBM25743 1-cycloheptyl-3-(1-acetylpiperidin-4-yl)urea::US8501783, 1645::Urea-based compound, 24

SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCCCCC1

InChI Key InChIKey=LTDFSPICBQXVRT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 25743   

TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25743(US8501783, 1645 | 1-cycloheptyl-3-(1-acetylpiperid...)
Affinity DataIC50: 3.49E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM25743(US8501783, 1645 | 1-cycloheptyl-3-(1-acetylpiperid...)
Affinity DataIC50: 27.6nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM25743(US8501783, 1645 | 1-cycloheptyl-3-(1-acetylpiperid...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM25743(US8501783, 1645 | 1-cycloheptyl-3-(1-acetylpiperid...)
Affinity DataIC50: 27nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed