BDBM25733 CHEMBL476614::Urea-based compound, 14::methyl 4-[(adamantan-1-ylcarbamoyl)amino]-2-hydroxybenzoate
SMILES COC(=O)c1ccc(NC(=O)NC23CC4CC(CC(C4)C2)C3)cc1O
InChI Key InChIKey=PXJSHQUWAKRZPH-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 25733
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta
University of Alberta
Affinity DataIC50: 30nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Human)
Department of Entomology and University of California Davis Cancer Center
Curated by ChEMBL
Department of Entomology and University of California Davis Cancer Center
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Human)
Department of Entomology and University of California Davis Cancer Center
Curated by ChEMBL
Department of Entomology and University of California Davis Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate after 10 mins by fluorescent assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Human)
Department of Entomology and University of California Davis Cancer Center
Curated by ChEMBL
Department of Entomology and University of California Davis Cancer Center
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins...More data for this Ligand-Target Pair