BDBM25729 1,3-bis(3,4-dichlorophenyl)urea::CHEMBL10835::US8815951, 299::Urea-based compound, 10

SMILES Clc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1Cl

InChI Key InChIKey=ZDPIZPXVHVYTOK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 25729   

TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25729(US8815951, 299 | CHEMBL10835 | 1,3-bis(3,4-dichlor...)
Affinity DataIC50: 480nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase 1(Mouse)
The Regents of The University of California

US Patent
LigandPNGBDBM25729(US8815951, 299 | CHEMBL10835 | 1,3-bis(3,4-dichlor...)
Affinity DataIC50: 700nMAssay Description:The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM25729(US8815951, 299 | CHEMBL10835 | 1,3-bis(3,4-dichlor...)
Affinity DataIC50: 260nMAssay Description:The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBifunctional epoxide hydrolase 2(Mouse)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM25729(US8815951, 299 | CHEMBL10835 | 1,3-bis(3,4-dichlor...)
Affinity DataIC50: 708nMAssay Description:Inhibitory activity against murine soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM25729(US8815951, 299 | CHEMBL10835 | 1,3-bis(3,4-dichlor...)
Affinity DataIC50: 257nMAssay Description:Inhibitory activity against human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM25729(US8815951, 299 | CHEMBL10835 | 1,3-bis(3,4-dichlor...)
Affinity DataIC50: 28.1nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed