BDBM2567 4-hydroxy-6-phenyl-3-(phenylsulfanyl)-2H-pyran-2-one::4-hydroxy-6-phenylpyranone 2::CHEMBL310487

SMILES Oc1cc(oc(=O)c1Sc1ccccc1)-c1ccccc1

InChI Key InChIKey=IOFIOWLRZOQXNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2567   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2567(CHEMBL310487 | 4-hydroxy-6-phenyl-3-(phenylsulfany...)
Affinity DataIC50: 3.00E+3nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pfizer

Curated by ChEMBL
LigandPNGBDBM2567(CHEMBL310487 | 4-hydroxy-6-phenyl-3-(phenylsulfany...)
Affinity DataIC50: 3.00E+3nMAssay Description:HIV-1 protease inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pfizer

Curated by ChEMBL
LigandPNGBDBM2567(CHEMBL310487 | 4-hydroxy-6-phenyl-3-(phenylsulfany...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed