BDBM255605 US9499561, 28

SMILES Nc1ncc(cn1)-c1nc(nc2c(CN3CCN(CC3)C(=O)CO)csc12)N1CCOCC1

InChI Key InChIKey=YEIOZQMKNMXRFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255605   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM255605(US9499561, 28)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description: 1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS. 2. Compound was formulated in 100% DMSO in a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM255605(US9499561, 28)
Affinity DataIC50: 38nMpH: 7.5 T: 2°CAssay Description: 1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS. 2. Compound was formulated in 100% DMSO in a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent