BDBM255599 US9499561, 20

SMILES CC(C)(O)C(=O)N1CCN(Cc2csc3c(nc(nc23)N2CCOCC2)-c2cnc(N)nc2)CC1

InChI Key InChIKey=BGXKNSHOJOBTQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255599   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM255599(US9499561, 20)
Affinity DataIC50: 46.2nMpH: 7.5 T: 2°CAssay Description: 1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS. 2. Compound was formulated in 100% DMSO in a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM255599(US9499561, 20)
Affinity DataIC50: 52nMpH: 7.5 T: 2°CAssay Description: 1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS. 2. Compound was formulated in 100% DMSO in a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent